Obsidian Odyssey] Light. Brain. Heart.

Obsidian Odyssey] Light. Brain. Heart.

Hi All,

Today is a historic day that I wanted to commemorate properly.

I was talking to my friend over lunch. How grateful I am that finally talking about 'consciousness' and 'the Universe' is a mainstream topic that is being genuinely appreciated by the public and not a side chat.

Funny thing...a while ago I read a Buddhist text saying the Universe is made of light and sound, mostly light, and that its expression is Om. And here we are a Nobel Prize for using light to speak directly to the cells of a living brain. I'm not saying it's the same thing, but it's hard not to smile at the echo.

Enjoy!


Key Highlights

  • Karl Deisseroth, Stanford neuroscientist and practising psychiatrist, took the Nobel call late at night just after lying down from working on a paper; his kids slept through it.
  • He called the honour unexpected and said his first thoughts were gratitude to the trainees, staff and collaborators worldwide behind the work.
  • The prize recognises optogenetics — using light to switch specific nerve cells on or off in living animals.
  • Why it matters: it gives scientists precise cause-and-effect control over biological systems that could previously only be observed.
  • Favourite example: pacing the heart at different rates and watching how that changes brain states and behaviour — showing body-to-brain signalling relevant to decision-making and psychiatric illness.
  • He still sees patients because hearing people describe their own altered mental states keeps him connected to what matters most and shapes his lab experiments and teaching.
  • He hopes the prize helps reduce stigma: psychiatric conditions exist on a spectrum, and the traits involved are rooted in human evolution, having once served a purpose.
  • His closing message: understanding that bigger picture can build empathy for people who suffer and often lack the words to explain it.