Obsidian Odyssey] Light. Brain. Heart.
Hi All,
Today is a historic day that I wanted to commemorate properly.
I was talking to my friend over lunch. How grateful I am that finally talking about 'consciousness' and 'the Universe' is a mainstream topic that is being genuinely appreciated by the public and not a side chat.
Funny thing...a while ago I read a Buddhist text saying the Universe is made of light and sound, mostly light, and that its expression is Om. And here we are a Nobel Prize for using light to speak directly to the cells of a living brain. I'm not saying it's the same thing, but it's hard not to smile at the echo.
Enjoy!
Key Highlights
- Karl Deisseroth, Stanford neuroscientist and practising psychiatrist, took the Nobel call late at night just after lying down from working on a paper; his kids slept through it.
- He called the honour unexpected and said his first thoughts were gratitude to the trainees, staff and collaborators worldwide behind the work.
- The prize recognises optogenetics — using light to switch specific nerve cells on or off in living animals.
- Why it matters: it gives scientists precise cause-and-effect control over biological systems that could previously only be observed.
- Favourite example: pacing the heart at different rates and watching how that changes brain states and behaviour — showing body-to-brain signalling relevant to decision-making and psychiatric illness.
- He still sees patients because hearing people describe their own altered mental states keeps him connected to what matters most and shapes his lab experiments and teaching.
- He hopes the prize helps reduce stigma: psychiatric conditions exist on a spectrum, and the traits involved are rooted in human evolution, having once served a purpose.
- His closing message: understanding that bigger picture can build empathy for people who suffer and often lack the words to explain it.
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